Fig. 2: Enantioselective unsymmetrical 1,2-diamination of indoles via the dearomative (4 + 2) reaction.
From: Azocarboxamide-enabled enantioselective regiodivergent unsymmetrical 1,2-diaminations
Reaction conditions: 1 (0.2 mmol), 2 (0.2 mmol), and CPA-7 (5 mol%) in CH2Cl2 (1 mL) at r.t. for 24 h, all dr > 20:1, isolated yields, ee values were determined by chiral stationary HPLC.
