Fig. 1: Summary of using Z. mobilis as the chassis for biochemical production.

The blue font in the pathway represents the key enzymes. The solid line represents a one-step reaction, while the dotted line indicates a multi-step reaction. The thick blue solid line represents the native recalcitrant ethanol pathway. 2,3-BDO 2,3-butanediol, DMAPP dimethylallyl diphosphate, DXP 1-deoxy-D-xylulose-5-phosphate, ED Entner-Doudoroff pathway, FPP farnesyl diphosphate, G3P glyceraldehyde-3-phosphate, G6P glucose-6-phosphate, GPP geranyl diphosphate, IPP isopentenyl diphosphate, MEP methylerythritol 4-phosphate pathway, PHB poly-3-hydroxybutyrate, PPP pentose phosphate pathway, TCA tricarboxylic acid cycle.