Fig. 1: Set up of the NMP platform coupled with the MSC-bioreactor. | Nature Communications

Fig. 1: Set up of the NMP platform coupled with the MSC-bioreactor.

From: A proof-of-concept study in small and large animal models for coupling liver normothermic machine perfusion with mesenchymal stromal cell bioreactors

Fig. 1

a Schematic diagram and b Picture of the NMP platform for small animal models coupled with the MSC-bioreactor. The bioreactor is perfused in a closed parallel circuit that includes a dedicated roller pump. A stopcocks for perfusion fluid collection is placed downstream the MSC-bioreactor and upstream the liver chamber. 1, Reservoir; 2, Waste; 3, Reinfusion; 4, Bioreactor peristaltic pump; 5, Bioreactor; 6, Pump MSCs side; 7, Liver peristaltic pump; 8, Membrane oxygenator; 9, Gas mixture; 10, Heating coil and bubble trap; 11, Pre-liver sampling; 12, Liver; 13, Post-liver sampling; 14; Bile collection. Abbreviations: MSCs mesenchymal stromal cells.

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