Fig. 7: Synthetic applicability, flexibility, and scalability of the biocatalytic platform.
From: Biocatalytic enantioselective formation and ring-opening of oxetanes
a Biocatalytic enantioselective dehalogenation of (rac)−1a and ring-opening of (rac)−1b are scaled up to gram-scale reactions. b Biocatalytic sequential dehalogenation and ring-opening reactions are conducted in a one-pot cascade manner. c Synthetic applications of chiral products are exemplified by representative transformations. See section 7-9 in the Supplementary Materials for detailed rection conditions.
