Fig. 6: In vivo haemostatic sealing in porcine injury bleeding model. | Nature Communications

Fig. 6: In vivo haemostatic sealing in porcine injury bleeding model.

From: Molecular self-assembly strategy tuning a dry crosslinking protein patch for biocompatible and biodegradable haemostatic sealing

Fig. 6

a Haemostatic treatment in a porcine liver bleeding model. A part of the liver lobe (ca. 50 mm in length) was cut off to establish the porcine liver bleeding model. TachoSil® and FgC6 patch were applied on the wound with manual compression until haemostasis achieved. b Haemostatic time and c blood loss following treatment of Surgicel® Fibrillar, Surgiflo®(Thrombin), TachoSil® and FgC6 patch in the porcine liver bleeding model (n = 5 independent injuries). d Haemostatic treatment in a porcine femoral artery bleeding model. A severe arterial haemorrhage was produced with 6 mm arteriotomy. Combat Gauze® and FgC6 patch were applied on the injured femoral artery with manual compression until haemostasis achieved. e Haemostatic time and f blood loss following treatment in the porcine femoral artery bleeding model (n = 6 independent injuries). Error bars, mean ± SD. P values are determined by two-sided Student’s t-test for b, c, e and f.

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