Fig. 9: A schematic representation of the CDK8-AHL10-SUVH2/9 molecular module in regulating plant salt stress responses. | Nature Communications

Fig. 9: A schematic representation of the CDK8-AHL10-SUVH2/9 molecular module in regulating plant salt stress responses.

From: Salt stress activates the CDK8-AHL10-SUVH2/9 module to dynamically regulate salt tolerance in Arabidopsis

Fig. 9

When CDK8 kinase activity is low under normal conditions, unphosphorylated AHL10 protein is stable and recruits SUVH2/9 proteins to the promoter regions containing MARs to maintain a high level of H3K9me2. This recruitment suppresses the transcription of salt-responsive genes. Upon sensing salt stress, CDK8 becomes activated and triggers the phosphorylation of AHL10 to promote AHL10 protein degradation. As AHL10 levels decline, the recruitment of SUVH2/9 is also diminished, leading to a decrease in H3K9me2 levels in the promoter regions containing MARs and facilitating the transcriptional activation of salt-responsive genes.

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