Fig. 8: Consistency of regional segmentations across MRI contrasts. | Nature Communications

Fig. 8: Consistency of regional segmentations across MRI contrasts.

From: Enabling new insights from old scans by repurposing clinical MRI archives for multiple sclerosis research

Fig. 8

Consistency of segmented regions or labels across multiple MRI contrasts measured by the intraclass Correlation Coefficients (ICCs). On the left, coloured brain maps depict all 19 brain region labels: CSF (Cerebrospinal Fluid), 3rd and 4th Ventricle, DGM (Deep Grey Matter), Pons, Brainstem, Cerebellar GM (Grey Matter), Temporal Lobe, Lateral Ventricle Frontal Horn, Lateral Ventricle, Ventral DC (Diencephalon), Optic Chiasm, Cerebellar Vermis, Corpus Callosum, Cerebral WM (White Matter), Frontal Lobe GM, Limbic Cortex GM, Parietal Lobe GM, and Occipital Lobe GM, along with MS (Multiple Sclerosis) Lesions. The right side presents ICC values ranging from 0 to 1 for these regions, providing a quantitative measure of the consistency across multiple MRI contrasts. Higher ICC values indicate greater consistency in the measurement of a particular brain region. Dots represent median intraclass Correlation Coefficient and error bars display 95% confidence intervals. A vertical dashed line marks the median intraclass Correlation Coefficient across all regions. PPMS dataset, baseline images, N = 699. Source data are provided as a Source Data file.

Back to article page