Fig. 1: Cryo-EM density for the human PELP1-WDR18-TEX10 ternary complex.
From: Molecular insights into the overall architecture of human rixosome
a Domain organizations of human rixosome subunits studied here, PELP1, WDR18, TEX10, LAS1L and NOL9. Each protein is given a different color, and the domains are labeled. b Gel filtration profile of the mixture of PELP1-WDR18 and TEX10 (Superose 6 Increase 3.2/300 column on an AKTA Micro). Inset: SDS PAGE gel of selected fractions. The experiment was done two times. Source data are provided as a Source Data file. c Cryo-EM density for the PELP1-WDR18-TEX10 ternary complex, colored according to panel a. Two TEX10 molecules are present. d Cryo-EM density after local refinement for TEX10, viewed after a 90° rotation around the horizontal axis from panel c. e Cryo-EM density for the PELP1-WDR18-TEX10 ternary complex, with only one TEX10 molecule. Panels c–e were produced with UCSF Chimera22.
