Fig. 9: Scarless healing effect of F/R gel on rabbit ear hyperplasia wounds.
From: A dynamically phase-adaptive regulating hydrogel promotes ultrafast anti-fibrotic wound healing
a Experimental illustration for modeling process of rabbit ear wounds infected with MRSA and the following animal experiments (created with BioRender.com). b Optical photos, simulated graphs, and c statistical data of wound healing changes from day 0 to 28 (n = 3 biologically independent samples). d Schematic diagram of the evaluation indicators related to scarring effect on rabbit ears. e Statistical data of SEI, scar thickness, scar bulge angle and color measurement (n = 3 biologically independent samples). f Ultrasonography (red dotted lines indicate hyperplastic scarring area), H&E staining, and Masson’s staining images of the rabbit ear wound tissues. g Analysis of collagen orientation distribution based on Masson’s staining images in f. Three independent experiments were performed and representative results are shown in b, f, g. Data are presented as mean ± SD and statistical significance was analyzed via two-way ANOVA with Tukey’s multiple comparison test. P value: *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.
