Fig. 5: Contact frequency of the 2-fold (2f) binding Fabs to the AAV9 capsid. | Nature Communications

Fig. 5: Contact frequency of the 2-fold (2f) binding Fabs to the AAV9 capsid.

From: Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts

Fig. 5

a The percentages of contacted capsid residues within variable region (VR)-III, -IV, -V, (b) -VI, -VII, and (c) VR-IX are shown for all 2-fold binding Fabs. d An AAV9 capsid surface representation with the binding frequency for any 2-fold binding Fabs is displayed which is colored according to the bar on the right.

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