Fig. 3: In vitro evaluation of biocompatibility, pro-healing, and anti-bacterial performances of BEWI.
From: A skin-interfaced three-dimensional closed-loop sensing and therapeutic electronic wound bandage
a Live/dead staining of NIH/3T3 cells cultured with different materials for 24, 48, and 72 h. b Cell viability calculated based on live/dead staining images (n = 3 independent replicates, mean value ± SD). c Cell proliferation evaluation via CCK-8 test (n = 3 independent replicates, mean value ± SD). d Scratch assay to analyze the migration ability of NIH/3T3 cells pretreated with BEWI. Control is the group without BEWI treatment. e Quantification of the scratch closure rate (n = 3 independent replicates, one-way two-sided analysis of variance test, **P  <  0.01, ***P  <  0.001, mean value ± SD). f Images of cultivated E. coli and S. aureus colonies onto Luria-Bertani (LB) agar plates after being treated with different materials. g Quantitative assessment of anti-bacterial rate of various materials against E. coli and S. aureus (n = 3 independent replicates, one-way two-sided analysis of variance test, mean value ± SD). For the E. coli group, ****P  <  0.0001, ***P  =  0.0003 and, *P  = 0.0211. For the S. aureus group, ****P  <  0.0001, ***P  =  0.0001, **P  =  0.0055 and, *P  = 0.0313.
