Extended Data Fig. 8: Structure comparison of AZG1tZ/pH7.4 and AZG1AF.
From: Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1
a, The intracellular-facing cavity shown in the cut-in side view in AZG1tZ/pH7.4 (left) and AZG1AF (right). b, The radii along the potential transport path for AZG1tZ/pH7.4 (pink) and AZG1AF (purple). c, Top 10 tZ molecules docked into AZG1AF. Side view of the superimposition of AZG1tZ/pH7.4 (pink) and AZG1AF (purple) when they are aligned at the transport ___domain. ECD, TM5, 6, and 12 are omitted for clarity. The zoomed-in view of the substrate binding site reveals that the binding configurations of tZ (purple) in AZG1AF are similar to that of tZ (blue) in the AZG1tZ/pH7.4 structure.
