Fig. 2: Association of 115 metabolites constituting the metabolomic signature with years since menopause and aging biomarkers. | npj Aging

Fig. 2: Association of 115 metabolites constituting the metabolomic signature with years since menopause and aging biomarkers.

From: Years since menopause and its metabolomic signature with biological aging in women at midlife: a population-based study

Fig. 2

Presented from left to right are metabolite weights in the metabolic signature, regression coefficients for YSM (changes in metabolites per YSM increment), and regression coefficients for aging biomarkers (ln(HR) per SD increase in metabolites). Elastic net analysis, multivariable linear models and logistic regression models were used respectively. Colors denote the association directions (red-positive and blue-inverse) and magnitudes (the darker the color, the stronger the magnitude); asterisks represent association significance (two stars indicated Bonferroni-corrected p < 0.05, and three stars indicated p < 0.001), and p < 0.05 was considered statistically significant. Telomere length (TL), allostatic load (AL), PhenoAge (PA).

Back to article page