Fig. 4: IF intervention changes the functional potential of the gut microbiota.

a In the volcano plot, each dot represents a KEGG Orthologues (KO) and is distinguished by color. KOs enriched before the experiment are shown in red, and KOs enriched after the intervention are shown in blue. b The X axis represents the reporter Z score, and the y axis represents the functional pathways. The pathways with Z-scores less than zero were enriched before intervention, and those with values above zero were enriched after the intervention. The darkness of the bars indicates the completeness of each pathway. c Heatmap of associations between the relative abundances of KOs and clinical parameters. Red represents positive correlation, whereas blue represents negative correlation. AI atherosclerosis index, AST aspartate aminotransferase; BFR body fat ratio, DBP diastolic blood pressure, γ-GT gamma-glutamyl transferase, LDL-C low-density lipoprotein cholesterol, TC total cholesterol, TG triglyceride.