Fig. 3: Macrophages exhibit increased adhesion, invasion, and cytotoxicity against the biofilm formed by ΔsaeRS. | npj Biofilms and Microbiomes

Fig. 3: Macrophages exhibit increased adhesion, invasion, and cytotoxicity against the biofilm formed by ΔsaeRS.

From: Staphylococcus aureus SaeRS impairs macrophage immune functions through bacterial clumps formation in the early stage of infection

Fig. 3

A Representative CLSM images of biofilms formed by different strains of S. aureus (Scale bar, 200 μm and 20 μm). B Quantification of the biomass within the biofilm via the crystal violet assay (n = 6 per group). C Representative CLSM images of macrophages co-cultured with biofilms formed by different strains of S. aureus (scale bar, 200 μm). D Bacterial loads and survival rates within different biofilm groups before and after co-culturing with macrophages (n = 6 per group). ** p ≤ 0.01, *** p ≤ 0.001. Data are presented as means ± SD. CLSM, confocal laser scanning microscopy.

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