Fig. 8 | npj Genomic Medicine

Fig. 8

From: Genome-wide identification of inter-individually variable DNA methylation sites improves the efficacy of epigenetic association studies

Fig. 8

Contents of regulatory elements in previous and proposed designs of target CpG sites. Enrichment for regulatory elements in each set of target CpG sites is shown. The ORs was estimated by comparing the proportions of CpG sites that overlapped with regulatory annotations in each set. The background proportion was calculated from all CpGs in the human reference genome (hg19). CGI CpG island, CpGiant SeqCap Epi CpGiant, DHS DNase I-hypersensitive site, H3K27ac histone H3 acetyl Lys27, H3K4me1 histone H3 monomethyl Lys4, H3K4me3 histone H3 trimethyl Lys4, HM450 HumanMethylation450, Rep, replication, RRBS reduced-representation bisulfite sequencing, SureSelect SureSelect Human Methyl-Seq, TFBS transcription factor binding site

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