Fig. 2: Distribution of HBV integration breakpoints within the human genomes of 27 samples.
From: Characteristics of Hepatitis B virus integration and mechanism of inducing chromosome translocation
a Distribution of integration breakpoints across the human genome of 27 samples. Each bar represents the sampling frequency of HBV integration breakpoints at a particular locus within the human genome (hg19). Histogram axis units represent the number of samples. Some loci with a high frequency of integration are denoted. b HBV integration within the Human genome of 27 HCC samples. Each line represents HBV integration. One end means HBV genome breakpoints, and the other represents the human genome breakpoints. Red line represents the breakpoints in hotspot genes (TERT, KMT2B, and POTEA).
