Fig. 2: Genomic characteristics of IKBKG and its detection analysis strategy. | npj Genomic Medicine

Fig. 2: Genomic characteristics of IKBKG and its detection analysis strategy.

From: An efficient molecular genetic testing strategy for incontinentia pigmenti based on single-tube long fragment read sequencing

Fig. 2

a Schematic representation of the IKBKG gene and its downstream pseudogene IKBKGP1. The IKBKG gene contains 10 exons (exons 1–10), while IKBKGP1 contains only 7 exons (exons 3–10). The gray square arrows represent the highly homologous regions, and the green boxes represent the non-homologous regions. The MER67B repeated sequences are shown as yellow boxes. b Diagram of the analysis pipelines. The left side shows the routine bioinformatic pipeline of stLFR, and the right side shows a specialized analysis pipeline for IP.

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