Fig. 4: Automatic ALPS ROI selection.

We used the “JHU ICBM tracts maxprob thr25 1 mm” atlas labels of superior longitudinal fasciculus and corticospinal tract, for the association and projection areas, respectively (a). We restricted these labels to the area on the top of the lateral ventricles and excluded parts close to the cortex (b). We then calculated a warp from the MNI152 space to each subject’s diffusion space (c) and transformed the masks (d). The images presented in steps c and d display fractional anisotropy-modulated diffusivity in the x (red), y (green), and z (blue) directions.