Fig. 3: CSFP promoted the osteogenic and angiogenic abilities of MSC through the regulation of β-Catenin. | npj Regenerative Medicine

Fig. 3: CSFP promoted the osteogenic and angiogenic abilities of MSC through the regulation of β-Catenin.

From: Cyclic pulsation stress promotes bone formation of tissue engineered laminae through the F-actin/YAP-1/β-Catenin signaling axis

Fig. 3

a IF staining of Osterix and VEGF-A. b β-CATENIN mRNA expression levels in the normal control (NC), β-Catenin-knockdown (β-Catenin siRNA), and β-Catenin-overexpression (β-Catenin OVE) cell models. c β-Catenin protein expression levels in the NC, β-Catenin siRNA, and β-Catenin OVE cell models. d The mean fluorescence intensity of Osterix and VEGF-A in the β-Catenin OVE group was statistically higher than that of the NC group. Conversely, those in the β-Catenin siRNA and β-Catenin-inhibition (XAV) groups were statistically lower than that of the NC group. e QRT-PCR analysis. Data are presented as mean ± SEM, and *P < 0.05 (experimental groups vs NC group).

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