Fig. 2: EC migration towards FP-TEBs is dependent on CXCR2.

a Quantitative polymerase chain reaction (qPCR) array on chemokine and receptor-related genes of FP-TEBs and TEBs incorporating hBMSCs (n = 3). b Representative immunostaining images with quantification of cell numbers in different FP-TEBs at 2 weeks postoperatively (n = 5). White arrows, staining-positive cells. Scale bar, 10 μm. c Representative immunostaining images with quantification of cell numbers in different implants at 2 weeks postoperatively (n = 5). White arrows, staining-positive cells. Scale bar, 10 μm. d qPCR array on chemokine and receptor-related genes in critical-size bone defects treated with TEBs and FP-TEBs incorporating mBMSCs at 2 weeks postoperatively (n = 3). e Representative images of migrated HUVECs in Transwell systems. Cell quantification is shown as a bar graph (n = 10). Scale bar,100 μm. f Representative images of wound healing assays. The rate of scratch wound closure is shown as a bar graph (n = 10). Scale bar, 200 μm. g Representative images of tube formation assays. The tube length is shown as a bar graph (n = 10). Scale bar, 100 μm. Data are presented as the mean ± SEM. **P < 0.01.