Fig. 2: Characterisation of the MSC secretome by LC-MS/MS. | npj Regenerative Medicine

Fig. 2: Characterisation of the MSC secretome by LC-MS/MS.

From: Proteomic profiling of iPSC and tissue-derived MSC secretomes reveal a global signature of inflammatory licensing

Fig. 2

a Venn diagram of the total number of secreted proteins in resting CM (teal) compared to licensed CM (coral). b Bar graph showing the numbers of proteins from resting (teal) and licensed (coral) CM annotated to the major GO biological process terms. c Heat map of proteomic profiles of MSC secretomes indicating protein intensity (red = more intense, blue = less intense). d PCA plot of relationships between MSC secretomes from different donors, sources and licensing phenotypes (iMSCs = yellow, UC.MSCs = green, AT.MSCs = purple, BM.MSCs = blue; resting MSCs = triangles, licensed MSCs = circles). Figures were generated using iDEP1.196.

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