Fig. 2: Immunosuppression-induced alteration of gut microbial community.

a LEfSe (Linear discriminant analysis (LDA) Effect Size) analysis for the gut bacterial genus predominant after immunosuppressive treatment. (b) The abundance of Dialister, Anaerovibrio, Faecalibacterium, and Streptococcus under immunosuppression by qPCR. (c) Correlation network of the gut microbiota in the genus level. The correlation was determined with Sparse Estimation of Correlations among Microbiomes (SECOM) (Pearson 2) filter with correlation more than 0.9 and p-value less than 0.01. The Wilcoxon signed-rank test was used to analyze data in (b).