Table 4 Medication differences in minimum spanning tree measures.

	df	F	p	Mean	SE
Antipsychotic medication effects on MST measures
Connectivity strength
Group	1126	0.524	0.470
BD/AP				0.641	0.006
BD/nAP				0.635	0.006
Diameter
Group	1126	0.817	0.368
BD/AP				0.112	0.002
BD/nAP				0.109	0.002
Kappa
Group	1126	<0.001	0.990
BD/AP				2.802	0.013
BD/nAP				2.802	0.013
Leaf fraction
Group	1126	0.008	0.929
BD/AP				0.467	0.003
BD/nAP				0.467	0.003
Lithium effects on MST measures
Connectivity Strength
Group	1131	3.702	0.057
BD/li+				0.632	0.005
BD/li−				0.648	0.008
Diameter
Group	1131	1.131	0.290
BD/li+				0.109	0.002
BD/li−				0.113	0.002
Kappa
Group	1131	0.972	0.326
BD/li+				2.800	0.013
BD/li−				2.819	0.014
Leaf fraction
Group	1131	0.150	0.699
BD/li+				0.466	0.003
BD/li−				0.469	0.003

Group differences were tested with ANCOVAs with age, sex, and education as covariates and the Benjamini–Hochberg FDR correction for multiple testing.
HC healthy controls, SCP subclinical psychosis, SCZ schizophrenia spectrum disorder, BD bipolar disorder with psychosis, BD/AP bipolar disorder with antipsychotic use, BD/nAP bipolar disorder without antipsychotic use, BD/li+ bipolar disorder with lithium use, BD/li− bipolar disorder without lithium use.

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