Fig. 4: Resting state connectivity; treatment by schizotypy interactions.

A–C HS group have reduced connectivity compared with LS in all networks, A lessened by amisulpride in DMN, B lessened by ulotaront in ASN, and C unaffected by treatment in right ECN. The histograms show group mean intensities (z-scores) of individual resting state networks identified from the independent component analysis. Significance values for treatment by schizotypy shown in A and B are from ANOVA with factors for treatment and schizotypy group. ASN anterior salience network, DMN default mode network, ECN executive control network. Error bars are standard errors of the mean.