Fig. 1: Characterizing AML stages by combining the state-transition approach with SA-based PaSSS analysis. | npj Systems Biology and Applications

Fig. 1: Characterizing AML stages by combining the state-transition approach with SA-based PaSSS analysis.

From: Transcriptome free energy can serve as a dynamic patient-specific biomarker in acute myeloid leukemia

Fig. 1

a Surprisal analysis, PaSSS calculation and (b) state-transition model are carried out as described in Methods. c Schematic representation of mapping free energy within the state-transition state-space and (d) construction of patient-specific dynamical models of AML progression.

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