Fig. 1: Design and in vitro characterization of VSV vectors. | npj Vaccines

Fig. 1: Design and in vitro characterization of VSV vectors.

From: A single dose of a vesicular stomatitis virus-based influenza vaccine confers rapid protection against H5 viruses from different clades

Fig. 1

a Schematic representation of VSV-HA vectors. N nucleoprotein, P phosphoprotein, M matrix protein, EBOV GP Ebola virus glycoprotein, L polymerase, sHAzip soluble HA protein with trimerization sequence, HAfl full-length HA protein. b Western Blot analysis confirmed the presence of HA, EBOV GP, and VSV M in the supernatant of infected Vero E6 cells. Relevant parts of the gels are shown. For uncropped gel images, see Supplementary Fig. 1. c Growth kinetics of VSVs propagated on Vero E6 cells. The mean and standard deviation of one experiment performed in triplicates are shown. Statistically significant differences are indicated (p < 0.0001 (****)).

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