Fig. 1: Live/dead-based whole-genome CRISPR/Cas9 screening.

A Schematic flowchart for RV live/dead-based loss-of-function CRISPR screening approach. Image was created using Adobe Illustrator. B Plot of the scores of -Log10(p value) of the top hits in the screen, sorted on the x-axis by gene Rank. C Plot of the scores of Log2(fold change) of the top hits in the screen, sorted on the x-axis by gene Rank.