Extended Data Fig. 6: LTA data for platelet treated with different ADP agonist concentrations.

a) Plot showing LTA signal of primary aggregation for platelets treated with ADP. LTA was accomplished using PAP-8E profiler prewarmed to 37 °C. The blank (0% aggregation) was set with PPP. b) Representative RICM, duplex rupture fluorescence (red) images for one donor washed platelets that were treated with ADP with concentrations ranging from 0.1 mM to 20 mM. Scale bar = 10 μm. MCATS signal for this data is shown in main Fig. 3.