Extended Data Fig. 7: The ITCH and SIAH2 E3 ubiquitin ligases do not mediate heat shock-induced LATS degradation.
From: Heat stress activates YAP/TAZ to induce the heat shock transcriptome

a, Knockdown of ITCH and SIAH2 does not block the heat shock-induced LATS1 degradation. Immunoblotting has been performed two times with similar results. b, Verification of ITCH&SIAH2 siRNA knockdown efficiency by RT-PCR. Data are presented as mean ± s.d.; n = 3 biologically independent samples. Two-way ANOVA test. Source data are available online.