Extended Data Fig. 7: Anorexia-associated body mass changes of human pancreatic cancer implanted mice.
a, Tumor volumes were increased in Panc1 and Capan1 implanted mice. n = 4 mice for three groups; 3 week *P = 0.049, 4 week *P = 0.049, 5 week *P = 0.033. b, Body mass were reduced in Panc1 and Capan1 implanted mice compared to the control mice. n = 4 mice for each group; 3 week Panc1 **P = 0.0014 and Capan1 *P = 0.049, 5 week Panc1 ***P < 0.0001 and Capan1 ***P < 0.0001. 6 week Panc1 ***P < 0.0001 and Capan1 ***P < 0.0001. c, Relaxin-INSL family mRNA expression levels in Capan1 cells. n = 3 biologically independent experiments; Rxn vs INSL3 **P = 0.003. Data are presented as the mean ± s.e.m. Statistical significance was determined with two-tailed Student’s t-test; *P < 0.05. Statistical source data.
