Extended Data Fig. 7: Vps genes involved in STING degradation and the termination of type I interferon response. | Nature Cell Biology

Extended Data Fig. 7: Vps genes involved in STING degradation and the termination of type I interferon response.

From: STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes

Extended Data Fig. 7

a, The data related to Fig. 4b are shown. The top 25 genes are highlighted in red. The genes that were also ranked within top 25 in ‘type I interferon assay’ are highlighted in bright red. b, The data related to Fig. 4c are shown. The top 25 genes are highlighted in blue. The genes that were also ranked within top 25 in ‘STING degradation assay’ are highlighted in bright blue. c, Knockdown efficiency of Vps genes. Cells were treated with the indicated siRNAs for 72 hours, and qRT-PCR was performed. Gapdh was used as an internal control. Data are presented as mean values +/− SEM. The sample size (n) represents the number of the biological replicates (c). Source numerical data are available in source data.

Source data

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