Extended Data Fig. 7: Rabbit-mouse neighborhood comparisons.
From: An atlas of rabbit development as a model for single-cell comparative genomics
a) Distribution of the number of cells within neighbourhoods of the rabbit (n = 5,253 neighborhoods) and mouse atlas (n = 14,034 neighborhoods). b) Same plot as in Fig. 3d shown for all cell types. c) Neighbourhoods of the mouse atlas (n = 14,034 neighborhoods) coloured according to their maximum correlation with any rabbit neighbourhood. General UMAP positions for a subset of cell types are shown. d) Maximum correlation scores, grouped by the scRNA-seq sample (N = 19 embryos) of each neighbourhood index cell. Samples are ordered by mean maximum correlation and coloured by the developmental stage.Annotations above the GD9 samples refer to the anatomical dissection. The lower and upper hinges of the boxplots relate to the first and third quartiles respectively. The center line denotes the median and the whiskers extend to the largest/smallest value no further than 1.5 times the inter-quartile range from the upper/lower hinge respectively. Outlier points are plotted if they exceed the ranges defined by the the upper and lower whiskers. The number of neighbourhoods linked to each sample and thus used to calculate each statistic is written along the x-axis. A - anterior section, M - mid section; P - posterior section; YS -yolk-sac/extraembryonic tissues; EP - embryo proper. Neighbourhood sizes, annotations and maximum correlation values are provided in the source data.
