Extended Data Fig. 1: Subcellular localization patterns of mechanosensitive channel DmPiezo, NompC, and Iav.
From: Drosophila TMEM63 and mouse TMEM63A are lysosomal mechanosensory ion channels
Representative images showing the expression patterns of DmPiezo (a), NompC (b), Iav (c) proteins and organellar markers. Each mCherry-tagged channel protein was co-expressed with LAMP1-GFP, Mito-YFP or GFP-SKL in S2 cells. The co-localization between the channel protein and organellar marker was quantified by Pearson’s correlation coefficient (PCC). Data shown are mean ± s.e.m. The numbers of cells are shown beneath the bars. Scale bar, 5 µm. Numerical data is available as source data.
