Extended Data Fig. 3: Sphingolipid changes in the cells of the human and mouse immune system.
From: A lipid atlas of human and mouse immune cells provides insights into ferroptosis susceptibility
a-f, Breakdown of the indicated sphingolipid features in human (a-c) and mouse (d-f) immune cells. Data are shown as mean + S.D and statistically significant differences in lipid features between cell types was determined by 1-way ANOVA with Tukey’s HSD test after false discovery rate correction (5%; Benjamini-Hochberg). P values for all pairwise comparisons are shown in Table S1 and Table S2. In a-c, the n value denoting the number of individual human donor for each cell type are as follows: 14 for naive B cells, CD4 TCM, CD8 TNaive, classical monocytes, intermediate monocytes, and basophils; 13 for Memory B cells, CD4 TNaive, CD4 TEM, CD8 TEM, non-classical monocytes, and eosinophils; 12 for CD8 TCM, CD56dim NK cells and CD56bright NK cells; 11 for neutrophils. In d-f, the n value denoting the number of mice for each cell type are as follows: 8 for B cells and CD8 T cells; 9 for CD4 T cells, eosinophils, Ly6Clo monocytes and NK cells; 10 for Ly6Chi monocytes and neutrophil.
