Extended Data Fig. 3: The subtype annotations of epithelial cells by label transfer.
From: A single-cell atlas of chromatin accessibility in mouse organogenesis
a, UMAP visualization of integrated results of cells from scATAC-seq (this study) and pseudocells from MOCA epithelial cells, colored by omics (left) and cell-type assignment (right). b, Aggregate chromatin accessibility profiles for 22 epithelial subtypes at several marker gene loci. c, Violin plot showing the expression of epithelial marker genes across 22 epithelial subtypes using an integrated gene expression matrix. d, Heatmap showing Pearson’s correlation coefficients between average gene activity scores and gene expression of the top 500 differentially expressed genes (selected from scRNA-seq) across 22 epithelial subtypes. Each row represents a cell type in scATAC-seq data, and each column represents a cell type in scRNA-seq data. e, Heatmaps of mean gene expression (left) or gene activity score (right) for the top 500 differentially expressed genes (selected from scRNA-seq) across 22 epithelial subtypes. Each row represents a gene. Source numerical data are provided as source data.
