Extended Data Fig. 6: Supplemental analyses of lineage-specific transcriptional regulators in mouse organogenesis.
From: A single-cell atlas of chromatin accessibility in mouse organogenesis
a, Hierarchical clustering of transcription factor (TF) motif based on Pearson correlation coefficients in average motif activity across 43 major cell types. b, TF footprints of several lineages or cell-type specific TF motifs in the 43 main cell types. The Tn5 insertion bias track is shown below. c, DNA binding-site motif of Klf family TFs from the CIS-BP database27. d, Violin plot showing the expression of Klf family genes across 43 main cell types using the scRNA-seq dataset of TOME9. e, UMAP showing the motif deviation scores of Klf family motifs. f, Violin plot showing the cognate gene expression of selected TF motifs in Fig. 3c across 43 major cell types in the TOME scRNA-seq dataset9. g, Spatial visualization of the expression of several lineages or cell-type specific genes from E10.5 to E13.5. Source numerical data are provided as source data.
