Extended Data Fig. 4: Quantitative analysis of proteins and metabolites in cells undergoing EMT.
From: CD44 regulates epigenetic plasticity by mediating iron endocytosis
a, Gene Ontology-term enrichment heatmap of proteins ranked by molecular function illustrating a bias towards proteins with oxidoreductase activity being increased in the mesenchymal cell state. n = 3 biologically independent experiments. Statistical analysis, Material and Methods. b, Western blots of selected proteins. Data representative of n = 3 biologically independent experiments. c, Heatmap of metabolites in cells treated with EGF for 60 h. n = 4 technical replicates. MDA-MB-468 cells throughout the figure and treated with EGF for 72 h unless stated otherwise.
