Extended Data Fig. 3: Bach1 deficiency does not affect numbers of myeloid cells in the lungs of mice at baseline. | Nature Microbiology

Extended Data Fig. 3: Bach1 deficiency does not affect numbers of myeloid cells in the lungs of mice at baseline.

From: BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility

Extended Data Fig. 3

(A–C) Total numbers of (A) AMs (Live/CD45ivneg/F4/80+CD64+/CD11b-/CD11c+/Siglec-F+), (B) IMs (Live/CD45ivneg/ F4/80+CD64+/CD11bhi/CD11c-/l°w/Siglec-F-), and (C) neutrophils (Live/CD45+/DUMP−/CD11b+Ly6G+) in the lungs of uninfected Bach1-/- and WT mice as measured by flow cytometry. Results are pooled from of three independent experiments performed (WT n = 10 vs Bach1-/- n = 9) and the data shown are presented as mean values ± SEM of the pooled samples for each group. Each symbol represents an individual animal from each group. Statistical significance was assessed by the Mann-Whitney test, two-tailed. (ns, not significant).

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