Extended Data Fig. 9: Implantation of soft neural probes in the mice brain.
From: 3D spatiotemporally scalable in vivo neural probes based on fluorinated elastomers
(a, b) Schematics showing the shuttle-driven implantation technique for elastomer-based brain probes. a, The brain probe held by a SU-8 plastic frame was transferred to the brain surface. b, Schematics showing the implantation steps (side view). (I) After positioning the probe on the brain surface, a tungsten shuttle (core diameter of 70 µm, conically etched at the tip) pokes through a hole at the top of the device and penetrates the brain tissue. (II) Once the desired depth of implantation is reached, the tungsten shuttle is withdrawn from the brain tissue. (III) The SU-8 plastic frame, lying on the surface of the brain, is removed before (IV) sealing the craniotomy area with dental cement. c, Shuttle-driven implantation during craniotomy. A soft brain probe is guided inside brain tissues by a tungsten shuttle which pokes through a circular hole at the top of the device. d, Schematic of measurement setup for head-fixed mouse.
