Extended Data Fig. 8: Sequence alignments for the Sth1 ATPase ___domain and HSA region.
From: Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome
a, Sequence alignment of the S. cerevisiae Sth1 ATPase ___domain to the homologous Snf2 ATPase ___domain of the same organism. Secondary structure elements are represented in orange according to the cryo-EM structure of the Snf2 ATPase (PDB entry 5Z3U)17. Residues modelled in the Snf2 structure are topped by a black line with helical regions shown as cylinders and sheet regions as arrows. The Sth1 residues modelled in this work are indicated with a black dashed line below. ATPase motifs are underlined. Invariant residues are coloured in dark blue and conserved residues in light blue. The alignment was generated with MSAProbs71 within the MPI Bioinformatics Toolkit60 and visualized using ESPript88. b, Sequence alignment of the HSA regions from S. cerevisiae homologues Sth1 and Snf2. Illustration and generation of the alignment as in a.
