Extended Data Fig. 9: scHCL analysis.
From: Construction of a human cell landscape at single-cell level
a, scHCL results for bulk human ES cell data (n = 17 samples). Each row represents one cell type in our reference. Each column represents a bulk sample. PCC was used to evaluate cell-type gene expression similarity. Red, high correlation; grey, low correlation. Some cell-type data come from published works, as denoted by first author name: Zhong20, Li25, Segerstolpe27, Baron29, VentoTormo37, Camp42, LaManno43, Han57. b, scHCL results for colorectal cancer organoid data (n = 15 samples), as in a. c, scHCL results for liver bud organoid data (n = 465 cells), as in a except that each column represents a single cell in the customer data set. d, scHCL results for cerebral organoid data (n = 508 cells), as in c. e, t-SNE map of single-cell data for day 20 embryoid bodies differentiated from human iPS cells (n = 9,140 cells). Cells are coloured according to cell-type cluster. f, scHCL results obtained using the data set of day 20 embryoid bodies differentiated from human iPS cells (n = 9,140 cells), as in c. g, Cell–cell correlation network for embryoid body. Each node represents a pseudo-cell in each cell type.
