Extended Data Fig. 1: Tumorigenicity of the cell lines and PCA of the RNA-seq datasets. | Nature

Extended Data Fig. 1: Tumorigenicity of the cell lines and PCA of the RNA-seq datasets.

From: Reply to: Transformation of naked mole-rat cells

Extended Data Fig. 1

a, Tumorigenicity of the cell lines. Cells not analysed in this study are indicated with a ‘-’. All transforming genes were driven by a retroviral LTR promoter. b–e, PCA of the RNA-seq datasets. PCA was done using the expression of 13,276 orthologous genes across all four species (mouse (b), blind mole rat (c), NMR (d) and human (e)). The first two principal components of each analysis were extracted. Values in parentheses indicate the variance explained by each of the principal components. L, SV40LT; R, HRAS(G12V); T, human TERT. All transgenes are driven by LTR promoters.

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