Extended Data Fig. 2: MOp consensus cell type taxonomy.
From: A multimodal cell census and atlas of the mammalian primary motor cortex
a, Cluster overlap heatmap showing the proportion of nuclei in each pair of species clusters that are mixed in the cross-species integrated space. Cross-species consensus clusters are indicated by labeled blue boxes. Mouse clusters (rows) are ordered by the mouse MOp transcriptomic taxonomy dendrogram37. Marmoset (left columns) and human (right columns) transcriptomic clusters38 are ordered to align with mouse clusters. Color bars at top and left indicate subclasses of within-species clusters. b-c, Genome browser view showing transcriptomic and epigenetic signatures for gene markers of Lamp5_2 (NFIX) and Pvalb_1 (TMEM132C) GABAergic neurons in human (b) and mouse (c). Yellow bars highlight sites of open chromatin and DNA hypomethylation in the cell type with corresponding marker expression.
