Extended Data Fig. 11: Transcriptome differences between X and Y bearing spermatids.
From: The molecular evolution of spermatogenesis across mammals
The heatmaps indicate transcript abundances of significantly enriched genes in X- and Y-bearing spermatids in the different species (a: human, b: mouse, c: opossum, d: platypus). The corresponding bar plots (genes in the same order) show the genes with significantly enriched expression in X- and Y-bearing cells, respectively using two-sided Wilcoxon rank-sum tests with Bonferroni correction (ordered according to increasing P-values) (see also lists in Supplementary Table 11). Genes marked with an asterisk are long non-coding RNAs. Genes in red are located on autosomes, those in black on sex chromosomes. “XLOC” denotes loci annotated in our previous work6; notably, only few XLOC loci (opossum: XLOC-076551, XLOC-076500, XLOC-076152, XLOC-076546) were found to have coding potential (as assessed by analyses based on ribosome profiling data generated in our previous work6), whereas all others likely represent lncRNAs.
