Extended Data Fig. 3: Mendelian randomization analysis of CHIP association with chronic liver disease. | Nature

Extended Data Fig. 3: Mendelian randomization analysis of CHIP association with chronic liver disease.

From: Clonal haematopoiesis and risk of chronic liver disease

Extended Data Fig. 3

a, Effect of genetic variants against exposure (CHIP) and outcome (cirrhosis). Effect estimates are oriented to CHIP-increasing alleles. b, Phenome-wide mendelian randomization analysis of CHIP with 22 phenotypes. MR analysis was performed using MR Base platform. Estimates were derived using inverse variance weighted meta-analysis using 90 independent variants associated with CHIP with p < 5 x 10−5.

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