Extended Data Fig. 8: Export factors interact with NPC. | Nature

Extended Data Fig. 8: Export factors interact with NPC.

From: Nuclear export of pre-60S particles through the nuclear pore complex

Extended Data Fig. 8

a, The map of NPC-trapped pre-60S particle displayed in a low threshold, highlighting numerous extra densities connected to export factors. These densities could be assigned to the central FG Nups and/or NTFs with/without cargoes (CFNC) including FG-repeats omitted from the wall of NPC. The eL19 and YBL028C obviously interact with the extra density, suggesting a possible role in direct interactions with the NPC. b–e, Local refinements of Gle2 (b), Mex67-Mtr2-2 (c), Mex67-Mtr2-3 (d) and Bud20 (e) further show the interactions between these export factors and the NPC.

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