Extended Data Fig. 6: Viral Gag particle release from WT and CHD1L knockout macrophages.
From: Africa-specific human genetic variation near CHD1L associates with HIV-1 load
Viral Gag particle release was measured by p24 ELISA assay on the culture supernatants at different time points post-transduction. The three graphs show independent biological replicates. A12 cells were not available for all time points. Data are reported as the average and standard deviation of duplicate p24 ELISA readings. In each independent replicate, C12 was significantly different from WT as determined by repeated measures ANOVA (1: F (6, 12) = 188.8, P < 0.0001, 2: F (5, 10) = 503.6, P < 0.0001, 3: F (5, 10) = 81.58, P < 0.0001).
