Extended Data Fig. 10: Proposed mechanism for translational regulation of non-uAUG-containing transcripts. | Nature

Extended Data Fig. 10: Proposed mechanism for translational regulation of non-uAUG-containing transcripts.

From: Pervasive downstream RNA hairpins dynamically dictate start-codon selection

Extended Data Fig. 10

a, Percentage comparison of translating uAUG-containing, non-uAUG-containing and all transcripts with increased or decreased translation efficiency after elf18 induction (TE-up or TE-down). TE-up: transcripts with upregulated TE (P value < 0.05, log2-transformed fold change > 0.16); TE-down: transcripts with downregulated TE (P value < 0.05, log2-transformed fold change < –0.16). b, GO enrichment analysis on the non-uAUG-containing transcripts. c, A proposed model of mAUG-ds-mediated translational regulation of non-uAUG-containing transcripts during PTI.

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