Extended Data Fig. 5: Changes in PSD composition during human V1 development.

a, Schematic illustrating the developmental stages of samples in the human V1 dataset. b, PCA plots of samples in the human V1 dataset colored by their age groups. c, Hierarchical clustering of the samples in the human V1 dataset based on proteins with differential abundance. d, Gene set enrichment analysis (GSEA) for individual age groups across species. NES, normalized enrichment score. Nominal P values were adjusted by the Benjamini and Hochberg method. e, Scaled abundance patterns (module eigengene values) of four protein modules in the human V1 dataset. f, Similarity matrices representing pairwise Pearson correlations between human PFC and human V1 samples.